Using gold nanoparticles to find cancer treatment targets
Exploiting gold nanoparticle as a probe to identify therapeutic targets
This study is looking at how tiny gold particles might help fight ovarian and pancreatic cancers by blocking tumor growth and making current treatments work better, so it's for anyone interested in new ways to tackle these tough cancers.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma Hlth Sciences Ctr NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-10994061 on NIH RePORTER |
What this research studies
This research explores the use of gold nanoparticles (GNPs) as a novel approach to identify and validate therapeutic targets in cancer. By interacting with proteins in biological fluids, these nanoparticles form a protective layer that influences their behavior in the body. The study focuses on how self-therapeutic GNPs can inhibit tumor growth and metastasis, particularly in ovarian and pancreatic cancers, by disrupting harmful cellular interactions and enhancing the effectiveness of existing treatments like cisplatin.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with ovarian or pancreatic cancer who may benefit from enhanced treatment strategies.
Not a fit: Patients with cancers that do not respond to the mechanisms targeted by this research may not receive any benefit.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments by identifying new therapeutic targets and improving existing therapies.
How similar studies have performed: Previous research has shown promising results using nanoparticles in cancer treatment, indicating potential for success with this approach.
Where this research is happening
Oklahoma City, United States
- University of Oklahoma Hlth Sciences Ctr — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Mukherjee, Priyabrata — University of Oklahoma Hlth Sciences Ctr
- Study coordinator: Mukherjee, Priyabrata
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.