Using gold nanoparticles to create a device that helps restore vision in people with retinal diseases
Gold nanoparticle Neurosensory Epiretinal Implant to Treat Photoreceptor Vision Loss
This study is testing a new device called the gold-nanoparticle neurosensory epiretinal stimulator, which aims to help people with retinal diseases regain some vision by using light to stimulate the cells in their eyes.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10675766 on NIH RePORTER |
What this research studies
This research investigates a novel implant called the gold-nanoparticle neurosensory epiretinal stimulator (GNES), designed to help restore vision in individuals suffering from retinal degenerative diseases. The GNES utilizes gold nanoparticles that generate voltage when exposed to specific wavelengths of light, stimulating remaining retinal ganglion cells without the need for external power sources or complex surgeries. The goal is to create a biocompatible device that can effectively excite these cells and improve visual function. Patients with retinal dystrophy or degeneration may benefit from this innovative approach to vision restoration.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with retinal degenerative diseases or conditions that lead to photoreceptor vision loss.
Not a fit: Patients with intact photoreceptors or those whose vision loss is not related to retinal ganglion cell dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option for patients with vision loss due to retinal diseases, potentially restoring some level of sight.
How similar studies have performed: While the use of gold nanoparticles in medical devices is a growing field, this specific approach to restoring vision through a neurosensory implant is relatively novel and has not been extensively tested in prior studies.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Hajrasouliha, Amir Reza — Indiana University Indianapolis
- Study coordinator: Hajrasouliha, Amir Reza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.