Using glucose levels to identify early Alzheimer's risk in people with prediabetes.

Who could benefit from this research

What this research studies

This research investigates how fluctuations in glucose levels can serve as a digital biomarker for early signs of Alzheimer's Disease (AD) in older adults who are at risk for Type 2 diabetes. By utilizing Continuous Glucose Monitoring (CGM) technology, the study aims to provide a more detailed understanding of how glucose variability affects cognitive function and the risk of developing AD. Participants will have their glucose levels monitored continuously, allowing researchers to identify patterns that may indicate cognitive decline. The goal is to enhance early detection and intervention strategies for those at risk.

Why it matters

Where this research is happening

• University of Maryland Baltimore County
  Baltimore, United States Active

Researchers

• Principal investigator: Khambaty, Tasneem — University of Maryland Baltimore County
• Study coordinator: Khambaty, Tasneem

Related research

Other NIH-funded projects on the same topics.

• Alzheimer’s and dementia risk in people with prediabetes or type 2 diabetes

  This grant aims to understand why some older adults with prediabetes or type 2 diabetes develop memory problems or dementia.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11585476

• Alzheimer’s and related dementia in older adults with prediabetes or type 2 diabetes

  This grant aims to understand why cognitive problems occur in people 65 and older who have prediabetes or type 2 diabetes, using data from a long-running diabetes study to identify what drives memory and thinking decline.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11537840

• Support for Monitoring and Remote Tracking for Prediabetes

  Aimed at helping adults with prediabetes use continuous glucose monitors (CGMs) through training and support from community health workers to improve self-management and prevent progression to diabetes.

  NIH research University of Houston · Houston, United States · NIH-11451569

• Effects of different exercise intensities on blood vessels and metabolism in prediabetes and diabetes

  This project tests how moderate and high-intensity interval exercise affects blood vessel and fat tissue function in male and female rats with prediabetes or diabetes.

  NIH research University of the Pacific-Stockton · Stockton, United States · NIH-11420736

• ONWARD: Helping teens and young adults with prediabetes and type 2 diabetes get the resources they need

  A study tests easy, in-clinic and post-visit resource help for teens and young adults with type 2 diabetes to address social needs that affect their health.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11416347

• Walking in greenspace and built environments for adults with prediabetes

  This study tests whether walking in parks or green spaces, compared to built environments, improves blood sugar and stress measures in adults with prediabetes.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11386681

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.