Using gentle vibrations to help improve sleep in older adults with Alzheimer's disease.
Sleep induction by repetitive mechanosensory stimulation.
This study is looking at how gentle vibrations can help older adults with Alzheimer's disease get better sleep, which might also help with their memory problems.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10608638 on NIH RePORTER |
What this research studies
This research investigates how repetitive mechanosensory stimulation, such as gentle vibrations, can induce sleep in older adults, particularly those suffering from Alzheimer's disease. The study aims to understand the mechanisms behind this phenomenon and how improved sleep can potentially alleviate memory deficits associated with sleep disruptions in Alzheimer's patients. By exploring the relationship between sleep and neurodegenerative diseases, the research seeks to develop effective interventions that could enhance sleep quality and overall well-being in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 21 and above who are diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients who are not diagnosed with Alzheimer's disease or who do not experience sleep disruptions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-invasive method to improve sleep quality and cognitive function in patients with Alzheimer's disease.
How similar studies have performed: Previous research has shown that mechanical stimulation can promote sleep in animal models, suggesting potential for success in human applications.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Koh, Kyunghee — Thomas Jefferson University
- Study coordinator: Koh, Kyunghee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.