NIH-funded research NIH-funded research

Using genetics to understand how environmental factors affect human health

Official title: Genetics as a tool to improve phenotypes and associations with human disease

Funded at University of Colorado Denver · NIH-10936970 · Data updated 2026-11-12

This study is looking at how our genes and the environment work together to affect our health, and it's designed to help scientists better understand the traits we can see and how they relate to different diseases.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 10, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$390,000
NIH project number1R35GM154792-01
Project IDNIH-10936970 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with a family history of diseases that may be influenced by genetic and environmental factors.

Less likely to help

Patients with conditions that are solely genetic and not influenced by environmental factors may not benefit from this research.

What this research studies

This research aims to leverage the unique aspects of the human genome to explore how environmental risk factors contribute to human diseases. The team will develop new methods to analyze and interpret phenotypes, which are observable traits or characteristics, and their connections to health markers. By improving the way these traits are derived and understood, the research seeks to identify risk factors and mechanisms related to various diseases, ultimately benefiting the broader scientific community and enhancing disease research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of diseases influenced by environmental factors.

How similar studies have gone: Previous research has shown promise in using genetic approaches to understand environmental impacts on health, indicating that this methodology is both relevant and potentially effective.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Cole, Joanne Burnette — University of Colorado Denver
  • Study coordinator: Cole, Joanne Burnette

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.