Using genetic testing to improve blood pressure management in African Americans
Integrated, Individualized, and Intelligent Prescribing (I3P) Clinical Trial Network
This study is looking at how sharing genetic test results can help African Americans with high blood pressure and kidney disease make better treatment choices, by comparing the effects of getting those results right away versus waiting, to see if it improves their health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11069604 on NIH RePORTER |
What this research studies
This research investigates how genetic testing can guide treatment decisions for hypertension and chronic kidney disease in African Americans. It involves two clinical trials that will compare the effects of immediate versus delayed access to genetic test results on blood pressure control. By focusing on individuals with high-risk APOL1 genetic variants, the study aims to tailor therapies based on genetic information, potentially leading to better health outcomes. Participants will be monitored for changes in blood pressure and medication effectiveness over a specified period.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American adults aged 21 and older who have hypertension, with or without chronic kidney disease.
Not a fit: Patients who do not identify as African American or those without hypertension or chronic kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for hypertension and chronic kidney disease in African Americans.
How similar studies have performed: Previous research has shown promise in using genetic testing to guide treatment decisions, particularly in populations with specific genetic risk factors, indicating a potential for success in this approach.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Peterson, Joseph F. — Vanderbilt University Medical Center
- Study coordinator: Peterson, Joseph F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.