Using genetic information to improve pain management in underserved communities in Indiana.
Implementing genomic medicine through pragmatic trials in diverse and underserved populations across Indiana.
This study is looking for people from diverse backgrounds who experience pain to help test how using genetic information can improve the way opioids are prescribed, making pain relief safer and more effective for everyone.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10442371 on NIH RePORTER |
What this research studies
This research aims to recruit minority and underserved patients to participate in pragmatic clinical trials that test how genetic information can guide opioid therapy for better pain control. By utilizing state-wide electronic health records, the study will identify and engage participants from diverse backgrounds, particularly those in federally-designated underserved areas. The project seeks to optimize opioid prescribing practices to enhance safety and effectiveness, addressing the opioid crisis in Indiana. A multi-disciplinary team will implement genomic medicine protocols and collaborate with healthcare partners to influence clinical practice.
Who could benefit from this research
Good fit: Ideal candidates for this research include minority and underserved patients experiencing pain who may benefit from personalized opioid therapy based on their genetic makeup.
Not a fit: Patients who do not experience pain or those who are not part of minority or underserved populations may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain management strategies for patients, particularly those from underserved populations.
How similar studies have performed: Previous research has shown promise in using pharmacogenetic approaches to optimize opioid therapy, indicating potential success for this study.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Skaar, Todd C. — Indiana University Indianapolis
- Study coordinator: Skaar, Todd C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.