Using genetic information to improve cancer treatment decisions
Official title: Pharmacogenomics to Catalyze Decision Support in Oncology Care
Funded at University of Chicago · NIH-11058536 · Data updated 2026-11-12
This study is looking at how understanding your genes can help doctors create a more personalized cancer treatment plan just for you, making chemotherapy and pain relief more effective and with fewer side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | June 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $867,396 |
| NIH project number | 5R01HG012273-03 |
| Project ID | NIH-11058536 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients who are about to begin chemotherapy or pain management treatment.
✕Less likely to help
Patients who are not undergoing cancer treatment or those with non-cancer-related pain may not benefit from this research.
What this research studies
This research investigates how genetic information can be used to personalize cancer treatment and pain management for patients. By analyzing patients' genetic profiles, the study aims to provide tailored recommendations for chemotherapy and pain medications, potentially reducing side effects and improving overall treatment outcomes. The approach involves preemptive genotyping, which means testing patients' genetics before starting treatment to guide medication choices and dosages. This could lead to more effective and safer cancer care for patients.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments, reducing side effects and improving pain management for patients.
How similar studies have gone: Previous research has shown promising results in using pharmacogenomics to tailor cancer treatments, indicating that this approach has potential for success.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: O'donnell, Peter Hugh — University of Chicago
- Study coordinator: O'donnell, Peter Hugh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.