Using genetic information to assess mental health risks in children and adolescents
Polygenic Risk Scores in Child and Adolescent Psychiatry: Ethical, Clinical, and Legal Implications
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-10911771
This study is looking at how genetic information can help find kids and teens who might be at risk for mental health issues like schizophrenia, depression, and autism, so that they can get support early on, while also considering the important ethical questions around using this kind of information.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10911771 on ClinicalTrials.gov |
What this research studies
This research investigates how polygenic risk scores (PRS) can be used to identify children and adolescents at risk for psychiatric disorders such as schizophrenia, depression, and autism spectrum disorders. By analyzing genomic data, the study aims to predict the likelihood of developing these conditions before symptoms appear, allowing for early intervention and monitoring. The research also addresses the ethical implications of using such predictive tools in psychiatry, particularly concerning stigma and potential misuse. The goal is to enhance the understanding of mental health risks and improve care for young individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adolescents aged 0-21 who may be at risk for psychiatric disorders based on genetic factors.
Not a fit: Patients who are not within the age range of 0-21 or those without a family history of psychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and intervention for psychiatric disorders in children and adolescents, potentially reducing the severity of these conditions.
How similar studies have performed: Other research has shown promise in using genetic risk scores for predicting psychiatric disorders, indicating that this approach has potential for success.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PEREIRA, STACEY — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: PEREIRA, STACEY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder