Using genetic and environmental data to improve asthma treatment across all ages
Official title: Better utilization of omics data to inform precision medicine for asthma throughout the life course
Funded at Brigham and Women's Hospital · NIH-11055460 · Data updated 2026-11-12
This study is looking at how your genes and things like infections can affect your asthma over time, so you can learn more about what triggers your asthma and get treatments that are better suited just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 15, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $679,228 |
| NIH project number | 5R01HL169300-02 |
| Project ID | NIH-11055460 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals of all ages who experience asthma or asthma exacerbations.
✕Less likely to help
Patients with asthma who do not have a genetic predisposition or environmental triggers may not benefit from this research.
What this research studies
This research investigates how genetic factors and environmental exposures, such as viral and bacterial infections, contribute to asthma exacerbations throughout a person's life. By utilizing advanced techniques like Phage ImmunoPrecipitation Sequencing (PhIP-Seq) and various omics approaches, the study aims to identify individual susceptibility to asthma attacks. Patients may benefit from a better understanding of their asthma triggers and more personalized treatment options based on their unique genetic and environmental profiles.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored asthma management strategies for patients.
How similar studies have gone: Previous research has shown promise in using omics data to inform personalized medicine, suggesting that this approach could yield significant insights for asthma management.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Lasky-Su, Jessica a — Brigham and Women's Hospital
- Study coordinator: Lasky-Su, Jessica a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.