Using gene editing in the fallopian tubes for new contraceptive methods

Investigating oviductal gene editing delivered via extracellular vesicles as a novel contraceptive

NIH-funded research Colorado State University · NIH-10914937

This study is testing a new, easy-to-use birth control method that uses gene editing to safely prevent pregnancy without surgery, aiming to help people who want to avoid unintended pregnancies.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionColorado State University NIH-funded
Lab location1 site (Fort Collins, United States)
Project IDNIH-10914937 on NIH RePORTER

What this research studies

This research explores a novel contraceptive method that utilizes gene editing delivered through extracellular vesicles to target the fallopian tubes. The goal is to create a non-surgical, easy-to-use contraceptive option that minimizes side effects and addresses the high rate of unintended pregnancies in the U.S. By focusing on specific genes involved in fertility, the research aims to develop a permanent contraception solution without the risks associated with surgical procedures. The approach leverages advanced CRISPR technology to achieve precise gene modifications.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals seeking permanent contraception who are interested in non-surgical options.

Not a fit: Patients who are not seeking contraception or those who prefer traditional contraceptive methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective, and less invasive contraceptive option for individuals seeking permanent birth control.

How similar studies have performed: While gene editing approaches like CRISPR have shown success in other medical applications, this specific use for contraception is novel and has not been extensively tested.

Where this research is happening

Fort Collins, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.