Using friendly bacteria to help heal diabetic foot wounds
Prevention of intracellular infection in diabetic wounds by commensal Staphylococcus epidermidis
['FUNDING_R01'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-11085919
This study is looking at how a friendly bacteria called Staphylococcus epidermidis can help heal diabetic foot ulcers and prevent infections, with the hope of finding new treatments to keep you healthy and reduce the chances of needing an amputation.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (CORAL GABLES, UNITED STATES) |
| Trial ID | NIH-11085919 on ClinicalTrials.gov |
What this research studies
This research investigates how the beneficial bacteria Staphylococcus epidermidis can help prevent infections and promote healing in diabetic foot ulcers. By understanding the relationship between this commensal bacterium and the immune response, the study aims to develop new treatments that enhance wound healing and reduce the risk of amputations. The approach involves analyzing the microbiome of diabetic patients and exploring how these bacteria can counteract harmful bacteria like Staphylococcus aureus. The ultimate goal is to create effective therapeutic strategies for patients suffering from diabetic foot complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have diabetic foot ulcers or are at risk of developing them.
Not a fit: Patients with non-diabetic foot wounds or those who do not have diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve healing outcomes for patients with diabetic foot ulcers and reduce the incidence of amputations.
How similar studies have performed: Previous research has shown promising results in using beneficial bacteria to improve wound healing, indicating that this approach may be effective.
Where this research is happening
CORAL GABLES, UNITED STATES
- UNIVERSITY OF MIAMI SCHOOL OF MEDICINE — CORAL GABLES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TOMIC-CANIC, MARJANA — UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- Study coordinator: TOMIC-CANIC, MARJANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.