Using focused ultrasound to treat pediatric brain tumors non-invasively
Feasibility of transcranial histotripsy for pediatric neuro-oncology applications using a hemispherical transducer
['FUNDING_R21'] · UNIVERSITY OF UTAH · NIH-10769855
This study is looking at a new, gentle way to treat brain tumors in kids using focused ultrasound, which can help break down the tumors without hurting them, making it safer for young patients.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10769855 on ClinicalTrials.gov |
What this research studies
This research investigates a new, non-invasive treatment method for pediatric brain tumors using focused ultrasound technology. The approach aims to liquefy tumor tissue without causing significant side effects, which is crucial for young patients. By employing a specialized hemispherical transducer, the study will explore how different acoustic pressures can effectively target and treat both benign and malignant tumors. The research will involve both laboratory and clinical assessments to ensure safety and efficacy in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are pediatric patients aged 0-11 years diagnosed with benign or malignant brain tumors.
Not a fit: Patients with brain tumors that are not amenable to non-invasive treatment or those who are outside the specified age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer, less invasive treatment option for children with brain tumors, reducing the risk of long-term complications.
How similar studies have performed: While focused ultrasound is a promising approach, this specific application in pediatric neuro-oncology is novel and has not been extensively tested in prior studies.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ODEEN, HENRIK CARL AXEL — UNIVERSITY OF UTAH
- Study coordinator: ODEEN, HENRIK CARL AXEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: childhood brain cancer, pediatric brain cancer