Using focused ultrasound to treat low back pain non-invasively

Focused Ultrasound Neuromodulation of Dorsal Root Ganglion for Noninvasive Mitigation of Low Back Pain

['FUNDING_OTHER'] · UNIVERSITY OF UTAH · NIH-10899680

This study is exploring a new, gentle way to help people with chronic low back pain by using focused ultrasound to target specific nerves, aiming to provide a safer and more effective option than traditional pain treatments.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF UTAH (nih funded)
Locations1 site (SALT LAKE CITY, UNITED STATES)
Trial IDNIH-10899680 on ClinicalTrials.gov

What this research studies

This research aims to develop a non-invasive treatment for chronic low back pain using focused ultrasound to target the dorsal root ganglion. By delivering precise acoustic energy under MRI guidance, the treatment seeks to modulate nerve activity and reduce pain sensation without the risks associated with traditional pain medications or invasive procedures. The study will involve establishing baseline data on pain responses and testing the ultrasound technique in animal models before considering human applications. Patients may benefit from a safer, more effective alternative to current pain management strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who experience chronic low back pain.

Not a fit: Patients with acute low back pain or those who do not respond to non-invasive treatments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective, and non-invasive treatment option for individuals suffering from chronic low back pain.

How similar studies have performed: Previous research has shown promise in using focused ultrasound for neuromodulation, indicating potential success for this novel approach.

Where this research is happening

SALT LAKE CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.