Using focused ultrasound to improve breast cancer treatment
Quantitative evaluation of focused ultrasound thermal therapy on immunogenic cell death in breast cancer
This study is looking at a new, non-invasive treatment using focused ultrasound to help boost the immune system's fight against triple negative breast cancer, which could make immunotherapy work better for patients like you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10997423 on NIH RePORTER |
What this research studies
This research investigates the use of focused ultrasound thermal therapy to enhance the immune response against triple negative breast cancer (TNBC). By inducing a specific type of cell death known as immunogenic cell death (ICD), the therapy aims to improve the effectiveness of immunotherapy in patients with TNBC. The approach is non-invasive and seeks to target tumors while minimizing systemic side effects associated with traditional chemotherapy. Patients may benefit from a novel treatment option that could lead to better outcomes in managing their cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with triple negative breast cancer who have not responded adequately to conventional therapies.
Not a fit: Patients with non-breast cancer diagnoses or those with breast cancer types other than triple negative may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, non-toxic treatment option that enhances the immune response against breast cancer, potentially improving survival rates.
How similar studies have performed: Previous research has shown promising results using immunogenic cell death in combination with other therapies, indicating potential for success with this novel approach.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Payne, Allison — University of Utah
- Study coordinator: Payne, Allison
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.