Using Fluorometholone to Improve Eyelid Surgery Outcomes for Trachoma Patients
Fluorometholone as Adjunctive Therapy for Trachomatous Trichiasis Surgery
This study is looking at how adding a medication called Fluorometholone to eyelid surgery can help people with trachomatous trichiasis, a condition that can cause blindness, by reducing the chances of the problem coming back after surgery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10659165 on NIH RePORTER |
What this research studies
This research investigates the use of Fluorometholone, a medication, as an adjunctive therapy to enhance the outcomes of eyelid surgery for patients suffering from trachomatous trichiasis, a complication of trachoma that can lead to blindness. The study aims to reduce the recurrence of trachomatous trichiasis after surgery, which currently affects a significant number of patients, particularly in impoverished areas. By providing this treatment alongside surgery, the research seeks to improve visual outcomes and reduce the need for repeat surgeries. Patients will be monitored for postoperative complications and the effectiveness of the treatment in preventing recurrence.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with trachomatous trichiasis who are scheduled to undergo eyelid surgery.
Not a fit: Patients who do not have trachomatous trichiasis or those who are not candidates for eyelid surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rates of postoperative complications and blindness among patients undergoing surgery for trachomatous trichiasis.
How similar studies have performed: Previous research has shown promising results in using adjunctive therapies to improve surgical outcomes, suggesting that this approach may be effective.
Where this research is happening
Boston, United States
- Massachusetts Eye and Ear Infirmary — Boston, United States (Active)
Researchers
- Principal investigator: Kempen, John H — Massachusetts Eye and Ear Infirmary
- Study coordinator: Kempen, John H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.