Using fibrin-based nanoparticles to improve blood vessel connections in surgery
Fibrin-Based Nanoparticles as a Novel Sealant for Vascular Anastomosis
This study is looking at a new way to help doctors connect blood vessels during surgeries, like organ transplants, by using special tiny particles that can help heal better and faster, making recovery easier for patients.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10912820 on NIH RePORTER |
What this research studies
This research focuses on enhancing the surgical technique of vascular anastomosis, which connects blood vessels during procedures like organ transplants and cardiovascular surgeries. The team is developing fibrin-based nanoparticles that can serve as a sealant, offering advantages over traditional fibrin glues by allowing for better healing, longer working times, and improved storage conditions. By optimizing these nanoparticles, the research aims to create a more effective surgical sealant that promotes faster recovery and reduces complications for patients undergoing these procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing surgeries that involve vascular anastomosis, such as organ transplants or cardiovascular surgeries.
Not a fit: Patients who are not undergoing surgical procedures involving blood vessel connections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more efficient surgical procedures with quicker recovery times for patients.
How similar studies have performed: Previous research has shown promise in using fibrin-based materials for surgical applications, indicating potential success for this novel approach.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Moiseiwitsch, Nina Alexandra — Univ of North Carolina Chapel Hill
- Study coordinator: Moiseiwitsch, Nina Alexandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.