Using fentanyl test strips to prevent opioid overdoses

Off-label Use of Rapid Response Fentanyl Test Strips as an Opioid Overdose Prevention Strategy

NIH-funded research Research Triangle Institute · NIH-10418675

This study is looking at how using fentanyl test strips can help people who inject drugs avoid overdoses by checking their drugs for fentanyl, and it aims to share what they learn with community groups and decision-makers to improve safety.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-10418675 on NIH RePORTER

What this research studies

This research investigates the use of fentanyl test strips (FTS) as a primary strategy to prevent opioid overdoses among individuals who inject drugs. The study employs a mixed-methods approach to explore both the positive and negative consequences of using these test strips in real-world settings. By distributing FTS, the research aims to empower users to test their drugs for the presence of fentanyl, thereby reducing the risk of overdose before it occurs. The findings will help inform community-based organizations and policymakers about the effectiveness of this intervention.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who inject drugs and are at risk of opioid overdose, particularly those using illicitly made fentanyl.

Not a fit: Patients who do not use injectable drugs or are not at risk of opioid overdose may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the number of opioid overdose deaths by providing users with a tool to identify dangerous substances in their drugs.

How similar studies have performed: Other research has shown promising results with similar harm reduction strategies, indicating that the use of fentanyl test strips could be an effective intervention.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Communicable DiseasesInfectious Disease PathwayInfectious DiseasesInfectious Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.