Using family health history to improve genetic risk assessment in diverse primary care settings
Deploying a genomic-medicine risk assessment model for diverse primary care populations and settings
This study is working to make it easier for families to share their health history so that doctors can better spot people at risk for inherited health issues, especially in diverse communities, by using a friendly online tool that encourages family involvement.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10918261 on NIH RePORTER |
What this research studies
This research aims to enhance the use of family health history (FHH) in identifying individuals at risk for hereditary conditions within diverse primary care populations. It addresses barriers to effective data collection and synthesis by developing a user-friendly, literacy-enhanced interface that encourages family engagement through social networking platforms. The project will create a comprehensive risk assessment and management system that is scalable and tailored for low-resource settings, ensuring that more patients can benefit from genetic testing and personalized care plans.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse backgrounds who may have limited access to genetic risk assessment services and those with a family history of hereditary conditions.
Not a fit: Patients who do not have a family history of hereditary conditions or those who are already receiving comprehensive genetic counseling may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification and management of hereditary health risks for patients, ultimately enhancing their health outcomes.
How similar studies have performed: Previous studies have shown that systematic family health history-based risk assessments can successfully identify a significant percentage of patients at risk for hereditary conditions, indicating a promising approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Orlando, Lori Ann — Duke University
- Study coordinator: Orlando, Lori Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.