Using external nerve stimulation to treat ADHD in children

Efficacy of External Trigeminal Nerve Stimulation for Treatment of ADHD

NIH-funded research University of California Los Angeles · NIH-11021040

This study is looking at whether a gentle, non-invasive treatment called external trigeminal nerve stimulation can help kids with ADHD feel better, especially for those who don’t do well with regular medications.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11021040 on NIH RePORTER

What this research studies

This research investigates the effectiveness of external trigeminal nerve stimulation (TNS) as a non-invasive treatment for attention-deficit/hyperactivity disorder (ADHD) in children. The study will involve a large, multisite randomized clinical trial to assess how well TNS can alleviate symptoms of ADHD compared to standard treatments. By focusing on understanding the underlying neural mechanisms of ADHD, the research aims to provide a reliable method for predicting treatment responses. This approach seeks to offer an alternative for children who may not respond well to traditional medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-21 who have been diagnosed with ADHD.

Not a fit: Patients who do not have ADHD or those who are older than 21 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for children with ADHD that minimizes the need for medication.

How similar studies have performed: While the use of neuromodulation techniques is gaining interest, this specific application of external trigeminal nerve stimulation for ADHD is relatively novel and has not been extensively tested in prior studies.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.