Using existing drugs to find new treatments for Alzheimer's disease
ADMINISTRATIVE SUPPLEMENT - TargetAD: A systems multi-omics approach to drug repositioning in Alzheimer's disease
This study is looking at how we can use already approved medications in new ways to help treat Alzheimer's disease by exploring the connections between different biological factors, with the goal of finding effective treatments for those living with the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11128137 on NIH RePORTER |
What this research studies
This research investigates how existing medications can be repurposed to treat Alzheimer's disease by analyzing complex biological data. It employs a multi-omics approach, which combines various biological data types to create a comprehensive network of molecular interactions related to Alzheimer's. By understanding these interactions, the research aims to identify which approved drugs could effectively target the underlying mechanisms of the disease. This innovative approach seeks to accelerate the discovery of potential therapies for Alzheimer's patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with late-onset Alzheimer's disease.
Not a fit: Patients with early-onset Alzheimer's disease or other forms of dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for Alzheimer's disease, potentially improving the quality of life for patients.
How similar studies have performed: Previous research has shown promise in drug repositioning for various conditions, indicating potential success for this novel approach in Alzheimer's treatment.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Krumsiek, Jan — Weill Medical Coll of Cornell Univ
- Study coordinator: Krumsiek, Jan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.