Using exenatide with nicotine patches to help people quit smoking and manage weight gain.
A Randomized Controlled Trial of Exenatide as an Adjunct to Nicotine Patch for Smoking Cessation and Prevention of Post-Cessation Weight Gain
This study is looking at how well using exenatide, a medication that helps with appetite and blood sugar, along with nicotine patches can help people quit smoking while also managing weight gain that often happens after quitting.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11101271 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of combining exenatide, a medication that helps regulate appetite and blood sugar, with nicotine patches to support individuals trying to quit smoking. The study focuses on addressing the common issue of weight gain that often occurs after quitting smoking, which can deter smokers from achieving abstinence. Participants will receive treatment and support to help them quit smoking while also managing their weight during the cessation process. The research aims to provide insights into how this combination therapy can improve smoking cessation outcomes and reduce post-cessation weight gain.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult smokers who are seeking to quit and may be concerned about weight gain after cessation.
Not a fit: Patients who are not smokers or those who do not have concerns about weight gain after quitting smoking may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help smokers quit while minimizing weight gain, thereby reducing the risk of obesity and related chronic illnesses.
How similar studies have performed: Previous pilot studies have shown promising results with similar approaches, indicating potential for success in this research.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Yammine, Luba — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Yammine, Luba
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.