Using epidural stimulation to improve breathing after spinal cord injuries
Cervical Epidural Stimulation and Respiratory Motor Plasticity
This study is looking at how using electrical stimulation on the spinal cord might help people with neck injuries breathe better on their own, which could mean less reliance on ventilators.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10875510 on NIH RePORTER |
What this research studies
This research investigates how epidural stimulation can help restore breathing functions in patients with cervical spinal cord injuries. By applying electrical stimulation to the spinal cord, the study aims to promote long-lasting changes in the respiratory system, potentially reducing the need for ventilator support. The approach focuses on understanding the mechanisms behind this stimulation and its effects on diaphragm activity. The research will involve both experimental and clinical conditions to assess the effectiveness of this treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cervical spinal cord injuries who experience respiratory compromise or failure.
Not a fit: Patients with spinal cord injuries at levels other than cervical or those without respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new therapeutic option for patients with respiratory issues due to cervical spinal cord injuries.
How similar studies have performed: Previous research has shown promise in using epidural stimulation for restoring motor functions, but this specific application for respiratory plasticity is novel.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Dale, Erica Arden — University of Florida
- Study coordinator: Dale, Erica Arden
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.