Using enhanced precautions to prevent the spread of antibiotic-resistant bacteria in nursing homes

Optimal Use of Enhanced Barrier Precautions in Nursing Homes to Prevent the Transmission of MDROs

NIH-funded research University of Maryland Baltimore · NIH-11037234

This study is looking at how wearing gowns and gloves can help keep nursing home residents safe from germs that are hard to treat, especially for those with chronic wounds or on ventilators, so that staff can focus on the residents who need the most protection without making their jobs harder.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11037234 on NIH RePORTER

What this research studies

This research investigates the use of enhanced barrier precautions (EBP) in nursing homes to prevent the transmission of multi-drug resistant organisms (MDROs). It focuses on the application of gowns and gloves during high-contact care activities for residents, particularly those with chronic wounds or devices. The study aims to better identify which residents are at the highest risk for MDRO transmission, especially chronic ventilator residents, to optimize the use of EBP and reduce unnecessary burdens on nursing home staff. By analyzing contamination levels on healthcare provider attire, the research seeks to refine guidelines for EBP implementation.

Who could benefit from this research

Good fit: Ideal candidates for this research are nursing home residents, particularly those with chronic ventilatory support or a history of MDRO colonization.

Not a fit: Patients who do not reside in nursing homes or those without chronic conditions requiring enhanced precautions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the transmission of antibiotic-resistant infections in nursing homes, improving patient safety and health outcomes.

How similar studies have performed: Previous research has shown that enhanced precautions can effectively reduce infection rates in healthcare settings, suggesting potential success for this approach in nursing homes.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.