Using engineered hydrogels to guide stem cell growth and healing
Engineering microscale hydrogel deposition to direct single stem cell differentiation
['FUNDING_R01'] · UNIVERSITY OF ILLINOIS AT CHICAGO · NIH-10761721
This study is looking at how special gels can help stem cells grow into bone cells, which could lead to better treatments for injuries, making it easier for patients to heal.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT CHICAGO (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-10761721 on ClinicalTrials.gov |
What this research studies
This research focuses on how engineered hydrogels can be used to control the growth and differentiation of mesenchymal stem cells (MSCs), which are important for regenerating damaged tissues. By precisely depositing hydrogels around individual stem cells, the researchers aim to enhance the cells' ability to develop into bone-forming cells. The study will explore how different gel properties affect stem cell behavior, potentially leading to more effective treatments for tissue injuries. Patients may benefit from advancements in stem cell therapies that are more predictable and effective.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions requiring tissue regeneration, such as bone injuries or degenerative diseases.
Not a fit: Patients with conditions unrelated to tissue regeneration or those who do not have access to stem cell therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved stem cell therapies for regenerating damaged bone and other tissues.
How similar studies have performed: Previous research has shown promise in using engineered hydrogels for stem cell applications, indicating a potential for success in this novel approach.
Where this research is happening
Chicago, UNITED STATES
- UNIVERSITY OF ILLINOIS AT CHICAGO — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHIN, JAE-WON — UNIVERSITY OF ILLINOIS AT CHICAGO
- Study coordinator: SHIN, JAE-WON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.