Using engineered hormones and stem cells to heal pressure ulcers
Official title: Overcoming pressure ulcers with engineered hormones and stem cells
Funded at Larix Bioscience, LLC · NIH-10821146 · Data updated 2026-11-12
This study is working on new treatments using hormones and stem cells to help heal pressure ulcers, especially for older adults and those with mobility challenges, so they can recover better and avoid getting these painful sores again.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Larix Bioscience, LLC NIH-funded |
| Lab location | 1 site (Sunnyvale, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $295,923 |
| NIH project number | 1R43AG085728-01 |
| Project ID | NIH-10821146 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include elderly individuals or those with physical impairments who are at risk of developing pressure ulcers.
✕Less likely to help
Patients who do not have pressure ulcers or are not at risk for developing them may not benefit from this research.
What this research studies
This research focuses on developing innovative hormonal therapeutics and stem cell approaches to enhance the healing of pressure ulcers, particularly in elderly and physically impaired individuals. The team aims to create stable hormone fusions and nanomedicines that can improve tissue regeneration and prevent the recurrence of these painful injuries. By addressing the underlying issues of poor tissue regeneration, the research seeks to provide a more effective treatment option for patients suffering from pressure ulcers.
Why it matters
Potential benefit: If successful, this research could significantly improve healing outcomes for patients with pressure ulcers, reducing pain and the risk of complications such as amputation.
How similar studies have gone: While the approach of using engineered hormones and stem cells is innovative, similar strategies in enhancing tissue regeneration have shown promise in other contexts, indicating potential for success.
Where this research is happening
-
Larix Bioscience, LLC
Sunnyvale, United States Active
Researchers
- Principal investigator: Hu, Mickey — Larix Bioscience, LLC
- Study coordinator: Hu, Mickey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.