NIH-funded research NIH-funded research

Using electronic tools to identify risks of opioid misuse and overdose

Official title: Feasibility of Electronic Screening to Identify Risk of Opioid Misuse and Overdose

Funded at Oprems LLC · NIH-10822394 · Data updated 2026-11-12

This study is testing a new digital way to help doctors and pharmacists better identify patients who might be at risk for misusing opioids, so they can provide the right support and education, especially about using naloxone to prevent overdoses.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOprems LLC
NIH-funded
Lab location1 site (Northbrook, United States)
Project startSeptember 15, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$295,876
NIH project number1R41DA060000-01
Project IDNIH-10822394 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include patients who are currently prescribed opioid medications and may be at risk for misuse.

Less likely to help

Patients who are not prescribed opioids or who do not have any risk factors for opioid misuse may not benefit from this research.

What this research studies

This research aims to enhance the screening process for patients prescribed opioids by transitioning from a paper-based system to a digital platform. By utilizing tablet PCs, the project seeks to improve the consistency and effectiveness of identifying individuals at risk for opioid misuse and overdose. The program, known as ONE, has already shown promising results in community pharmacies, where it has significantly increased the dispensing of naloxone, a medication that can reverse opioid overdoses. The goal is to provide targeted interventions and education to patients based on their screening results.

Why it matters

Potential benefit: If successful, this research could lead to more effective prevention strategies for opioid misuse and overdose, ultimately saving lives.

How similar studies have gone: Previous implementations of the ONE program have shown success in increasing naloxone dispensing rates, indicating that similar approaches may be effective.

Where this research is happening

  • Oprems LLC
    Northbrook, United States
    Active

Researchers

  • Principal investigator: Ferrarese, Nick — Oprems LLC
  • Study coordinator: Ferrarese, Nick

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.