NIH-funded research Career grant

Using electronic cigarettes to help people with opioid use disorder reduce smoking

Official title: Electronic Cigarettes as a Harm Reduction Strategy Among People with Opioid Use Disorder on Buprenorphine

Funded at Clemson University · NIH-11113411 · Data updated 2026-11-12

This study is looking at how electronic cigarettes might help people with opioid use disorder, who are being treated with buprenorphine, to cut down on regular cigarette smoking, and it aims to create helpful guidelines for using e-cigarettes in clinics.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionClemson University
NIH-funded
Lab location1 site (Clemson, United States)
Project startJune 15, 2025
Project endMay 31, 2030
Funding year2025
Award (this year)$176,754
NIH project number1K01DA062708-01
Project IDNIH-11113411 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who are currently undergoing treatment for opioid use disorder with buprenorphine and are also smokers.

Less likely to help

Patients who do not smoke or are not undergoing treatment for opioid use disorder may not receive any benefit from this research.

What this research studies

This research investigates how electronic cigarettes can serve as a harm reduction tool for individuals with opioid use disorder who are being treated with buprenorphine. The project aims to develop and implement effective protocols for using electronic cigarettes in clinical settings to help reduce the reliance on combustible cigarettes. The research will involve a multidisciplinary mentorship team and will utilize various methods, including qualitative and quantitative assessments, to evaluate the impact of electronic cigarettes on smoking behaviors among this population.

Why it matters

Potential benefit: If successful, this research could provide a safer alternative for individuals with opioid use disorder to reduce their smoking habits and improve their overall health.

How similar studies have gone: Previous research has shown that electronic cigarettes can help reduce smoking rates in the general population, suggesting potential for similar success in this specific group.

Where this research is happening

  • Clemson University
    Clemson, United States
    Active

Researchers

  • Principal investigator: Pericot-Valverde, Irene — Clemson University
  • Study coordinator: Pericot-Valverde, Irene

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.