Using electrodes to stimulate the spinal cord for restoring sensation in amputees
Electrodes for selective stimulation of the lateral spinal cord to restore sensation after lower-limb amputation
This study is working on creating better electrodes that can help people with lower-limb amputations feel sensations in their missing leg, which could make it easier for them to balance and move around safely.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11046662 on NIH RePORTER |
What this research studies
This research focuses on developing advanced electrodes that can selectively stimulate the lateral spinal cord to restore sensory feedback in individuals with lower-limb amputations. By improving the design and flexibility of these electrodes, the goal is to generate more precise sensations in the missing limb, which could enhance balance and mobility. The approach involves a combination of animal experiments, neurophysiology, and computational modeling to optimize the electrode design and understand how the spinal cord responds to stimulation. Patients may benefit from improved prosthetic limb functionality and reduced risk of falls.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have undergone lower-limb amputation and are seeking improved prosthetic functionality.
Not a fit: Patients who have not experienced lower-limb amputation or those with conditions that prevent them from using prosthetics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for amputees by restoring sensory feedback and enhancing mobility.
How similar studies have performed: Previous studies have shown promising results with similar approaches in restoring sensation through spinal cord stimulation, indicating potential for success in this novel application.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Fisher, Lee E — University of Pittsburgh at Pittsburgh
- Study coordinator: Fisher, Lee E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.