Using electrochemical methods to add fluorine to organic compounds
Official title: Electrochemical Fluorination for Organic Synthesis
Funded at Purdue University · NIH-11069497 · Data updated 2026-11-12
This study is exploring a new way to add special fluorine groups to certain compounds to make them better for use as medicines, which could help improve how they work in the body and lead to new treatments.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project start | June 1, 2025 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31GM154474-01A1 |
| Project ID | NIH-11069497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would be individuals with conditions that could benefit from new drug therapies developed through advanced organic synthesis techniques.
✕Less likely to help
Patients who are not seeking new therapeutic options or those with conditions that do not respond to drug therapies may not benefit from this research.
What this research studies
This research focuses on the electrochemical fluorination of organic compounds, which can significantly alter their properties and improve their effectiveness as drugs. By selectively adding fluorinated groups to these compounds, the study aims to enhance their pharmacological profiles, making them more suitable for therapeutic use. The approach involves developing new synthetic methods that can work under mild conditions, allowing for the creation of innovative drug candidates and biological probes. This research could lead to a better understanding of how these modified compounds interact with proteins and enzymes in the body.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective and safer therapeutic agents for various medical conditions.
How similar studies have gone: Other research in the field of medicinal chemistry has shown success in using fluorination to enhance drug properties, indicating that this approach has potential for impactful results.
Where this research is happening
-
Purdue University
West Lafayette, United States Active
Researchers
- Principal investigator: Bay, Jessica — Purdue University
- Study coordinator: Bay, Jessica
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.