Using electrical pulses to treat liver tumors
Development and application of non-thermal high frequency IRE to treat hepatic tumors
This study is looking at a new way to treat liver tumors using quick electrical pulses that can kill cancer cells while keeping healthy tissue safe, and it's designed for patients who can't have regular surgery or other common treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11013635 on NIH RePORTER |
What this research studies
This research investigates a novel treatment for liver tumors using irreversible electroporation (IRE), which involves delivering rapid electrical pulses to the tumor. This method creates permanent defects in the cell membranes of cancer cells, leading to their death without significant damage to surrounding healthy tissue. The goal is to provide a viable treatment option for patients who are not candidates for traditional surgical interventions or thermal ablation. By exploring this innovative approach, the research aims to improve outcomes for patients with advanced liver tumors.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with liver tumors who are not suitable for surgery or thermal ablation due to various factors.
Not a fit: Patients with early-stage liver tumors who can undergo surgical resection or thermal ablation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a new, effective treatment option for patients with liver tumors who currently have limited choices.
How similar studies have performed: Previous research has shown promising results with similar electroporation techniques in treating various tumors, indicating potential for success in this novel application.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Davalos, Rafael Vidal — Georgia Institute of Technology
- Study coordinator: Davalos, Rafael Vidal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.