NIH-funded research NIH-funded research

Using EEG to improve diagnosis of Parkinson's disease

Official title: Linear predictive coding of EEG Activity for Diagnosis of Parkinson's Disease (LEAD-PD)

Funded at University of Iowa · NIH-10659447 · Data updated 2026-11-12

This study is looking to create a new way to diagnose Parkinson's disease by using a quick brain scan that measures brain activity, helping doctors tell it apart from other similar conditions, so patients can get better care and track their progress more easily.

More s Disease research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Iowa
NIH-funded
Lab location1 site (Iowa City, United States)
Project startJune 1, 2023
Project endMay 31, 2026
Funding year2023
Award (this year)$1,876,731
NIH project number1RF1NS127809-01A1
Project IDNIH-10659447 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals experiencing symptoms of Parkinson's disease or those diagnosed with PD who are seeking better management of their condition.

Less likely to help

Patients with movement disorders that are not related to Parkinson's disease may not benefit from this research.

What this research studies

This research aims to develop a new method for diagnosing Parkinson's disease (PD) by analyzing brain activity through EEG (electroencephalography). The approach utilizes machine learning to identify specific patterns in EEG data that can differentiate PD from other similar movement disorders. By capturing critical differences in brain activity within just five minutes of resting data, the study seeks to provide a reliable biomarker for diagnosing PD and tracking its progression over time. This could lead to more accurate assessments of treatment responses and symptom management for patients.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of Parkinson's disease, improving treatment outcomes for patients.

How similar studies have gone: Preliminary results from similar approaches have shown promise, with the LEAD-PD method achieving over 85% sensitivity and specificity in diagnosing Parkinson's disease.

Where this research is happening

  • University of Iowa
    Iowa City, United States
    Active

Researchers

  • Principal investigator: Uc, Ergun Y — University of Iowa
  • Study coordinator: Uc, Ergun Y

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.