Using EEG to improve diagnosis of Parkinson's disease

Linear predictive coding of EEG Activity for Diagnosis of Parkinson's Disease (LEAD-PD)

NIH-funded research University of Iowa · NIH-10659447

This study is looking to create a new way to diagnose Parkinson's disease by using a quick brain scan that measures brain activity, helping doctors tell it apart from other similar conditions, so patients can get better care and track their progress more easily.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10659447 on NIH RePORTER

What this research studies

This research aims to develop a new method for diagnosing Parkinson's disease (PD) by analyzing brain activity through EEG (electroencephalography). The approach utilizes machine learning to identify specific patterns in EEG data that can differentiate PD from other similar movement disorders. By capturing critical differences in brain activity within just five minutes of resting data, the study seeks to provide a reliable biomarker for diagnosing PD and tracking its progression over time. This could lead to more accurate assessments of treatment responses and symptom management for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing symptoms of Parkinson's disease or those diagnosed with PD who are seeking better management of their condition.

Not a fit: Patients with movement disorders that are not related to Parkinson's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of Parkinson's disease, improving treatment outcomes for patients.

How similar studies have performed: Preliminary results from similar approaches have shown promise, with the LEAD-PD method achieving over 85% sensitivity and specificity in diagnosing Parkinson's disease.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.