NIH-funded research Sbir 2 grant

Using ear stimulation to help people stay in treatment for opioid use disorder

Official title: Delivering Transcutaneous Auricular Neurostimulation to Improve Treatment Retention in Opioid Use Disorder

Funded at Spark Biomedical INC · NIH-10456147 · Data updated 2026-11-12

This study is looking at a gentle ear stimulation technique to help people with opioid use disorder stick with their treatment and feel better, offering a safer and easier option than some traditional methods.

More Opioid Use research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSpark Biomedical INC
NIH-funded
Lab location1 site (Friendswood, United States)
Project startAugust 1, 2021
Project endJuly 31, 2025
Funding year2022
Award (this year)$1,246,700
NIH project number5R44DA053876-02
Project IDNIH-10456147 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with opioid use disorder who are seeking treatment options.

Less likely to help

Patients who are not struggling with opioid use disorder or those who are already successfully managing their condition may not benefit from this research.

What this research studies

This research investigates the use of transcutaneous auricular neurostimulation, a non-invasive technique that stimulates specific nerves in the ear, to improve treatment retention for individuals with opioid use disorder. The approach aims to provide a safe and effective alternative to traditional opioid withdrawal treatments, which often have limited availability and can pose significant risks. By focusing on a method that requires minimal training and has a low side effect profile, the research seeks to make treatment more accessible and effective for patients. Participants may receive this innovative therapy as part of their ongoing care to help manage their condition and reduce reliance on opioids.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment retention and outcomes for patients struggling with opioid use disorder.

How similar studies have gone: Other research has shown promise in using non-invasive neurostimulation techniques for various conditions, suggesting potential for success in this novel application.

Where this research is happening

  • Spark Biomedical INC
    Friendswood, United States
    Active

Researchers

  • Principal investigator: Khodaparast, Navid — Spark Biomedical INC
  • Study coordinator: Khodaparast, Navid

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.