Using Dronabinol to treat obstructive sleep apnea in veterans

Targeted Treatment of Obstructive Sleep Apnea with Dronabinol: Proof of Concept and Phase II Clinical Trial

['FUNDING_OTHER'] · JESSE BROWN VA MEDICAL CENTER · NIH-10923565

This study is looking at how well Dronabinol, a cannabis-based medication, can help veterans with obstructive sleep apnea, and it aims to find out which veterans might benefit the most from this treatment.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJESSE BROWN VA MEDICAL CENTER (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-10923565 on ClinicalTrials.gov

What this research studies

This research investigates the use of Dronabinol, a medication derived from cannabis, to treat obstructive sleep apnea (OSA) in veterans. The study aims to develop a prediction model to identify which patients are most likely to benefit from Dronabinol treatment based on their sleep study results and clinical characteristics. Initially, a proof-of-concept phase will assess the medication's effectiveness, followed by a randomized controlled trial to evaluate its efficacy over a longer treatment period. The goal is to provide a non-invasive treatment option for veterans suffering from OSA.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans diagnosed with moderate to severe obstructive sleep apnea.

Not a fit: Patients who do not have obstructive sleep apnea or those who are not veterans may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could offer a new, effective medication for veterans with obstructive sleep apnea, improving their quality of life and reducing associated health risks.

How similar studies have performed: Previous studies have shown some success with Dronabinol in improving OSA symptoms, but this research aims to refine the approach and validate its effectiveness in a larger veteran population.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.