Using doxycycline to prevent sexually transmitted infections in Kenyan women on HIV prevention medication
PrEP and dPEP: Doxycycline post-exposure prophylaxis for prevention of sexually transmitted infections among Kenyan women using HIV pre-exposure prophylaxis
This study is looking at whether taking doxycycline can help Kenyan women who are on HIV prevention medication (PrEP) avoid getting sexually transmitted infections (STIs), so they can take charge of their sexual health and reduce their risk of complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10682572 on NIH RePORTER |
What this research studies
This research investigates the use of doxycycline as a post-exposure prophylaxis (dPEP) to prevent sexually transmitted infections (STIs) among Kenyan women who are taking HIV pre-exposure prophylaxis (PrEP). The study aims to evaluate the effectiveness of dPEP in reducing the incidence of bacterial STIs, which have been found to be high in populations using PrEP. By focusing on a woman-controlled approach, the research seeks to empower women in managing their sexual health and reducing the risk of complications associated with STIs.
Who could benefit from this research
Good fit: Ideal candidates for this research are Kenyan women who are at risk for STIs and are currently using HIV PrEP.
Not a fit: Patients who are not using HIV PrEP or who do not have a risk of STIs may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rates of STIs among women using PrEP, leading to better overall health outcomes.
How similar studies have performed: Previous studies have shown promising results with similar approaches, particularly among men who have sex with men, indicating potential for success in this population as well.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Baeten, Jared — University of Washington
- Study coordinator: Baeten, Jared
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.