Using digital technology to analyze kidney biopsies in lupus nephritis patients
Digital Pathology and Computational Image Analysis for Lupus Nephritis
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11049028
This study is looking to make it easier and more accurate to diagnose and manage kidney problems caused by lupus, especially for patients of African ancestry, by using advanced technology to better understand kidney biopsies and help doctors catch issues early so they can provide better care.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11049028 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the diagnosis and management of lupus nephritis, a serious kidney condition associated with systemic lupus erythematosus. By utilizing digital pathology and advanced image analysis techniques, the study aims to enhance the accuracy and reliability of kidney biopsy interpretations. This innovative approach seeks to identify patients at risk of disease progression, potentially shifting treatment strategies from reactive to preventive care. The research will involve analyzing large cohorts of patients, particularly those of African ancestry, to ensure comprehensive and applicable findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults diagnosed with systemic lupus erythematosus who are experiencing or at risk for lupus nephritis.
Not a fit: Patients with lupus nephritis who are not of African ancestry or those who do not meet the age criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of lupus nephritis patients at risk for severe kidney complications, allowing for earlier intervention and improved patient outcomes.
How similar studies have performed: Other research has shown promising results using digital pathology in various medical fields, indicating potential for success in this novel application for lupus nephritis.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HODGIN, JEFFREY BENTON — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: HODGIN, JEFFREY BENTON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.