Using digital signals to detect Alzheimer's disease and related dementias

Novel application of Digital signals of movement, sleep and heart rhythms for detection of Alzheimer's Disease and Related Dementias

NIH-funded research Johns Hopkins University · NIH-10880669

This study is looking at how tracking your movement, sleep, and heart rhythms with wearable devices can help spot early signs of Alzheimer's and related memory issues, so we can find ways to help older adults before symptoms show up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10880669 on NIH RePORTER

What this research studies

This research investigates how changes in movement, sleep, and heart rhythms can help detect Alzheimer's disease and related dementias (ADRD) earlier. By utilizing wearable technology to collect data on physical activity and heart function, along with cognitive assessments and brain imaging, the study aims to identify patterns that may indicate cognitive decline before clinical symptoms appear. The approach is noninvasive and seeks to create scalable tools that can be used widely among older adults. The research will analyze data from over 1,000 participants to uncover connections between these digital signals and brain health.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who may be experiencing cognitive impairment or are at risk for Alzheimer's disease and related dementias.

Not a fit: Patients who are not older adults or those without any cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate detection of Alzheimer's disease and related dementias, allowing for timely interventions.

How similar studies have performed: Other research has shown promise in using digital signals for health monitoring, suggesting that this approach could be effective for detecting cognitive decline.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease detectionAlzheimer's disease and related dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.