Using digital signals from movement, sleep, and heart rhythms to find early signs of Alzheimer's and related dementias

Novel application of Digital signals of movement, sleep and heart rhythms for detection of Alzheimer's Disease and Related Dementias

NIH-funded research Johns Hopkins University · NIH-11132722

This project explores how digital information from your daily movements, sleep patterns, and heartbeats can help us find early signs of Alzheimer's disease and related dementias.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11132722 on NIH RePORTER

What this research studies

This project aims to find early signs of Alzheimer's disease and related dementias (ADRD) before symptoms become obvious. Researchers believe that changes in movement, sleep, and heart rhythms might be early indicators of these conditions. They will use wearable devices to collect digital information on these patterns from over 1000 older adults. This data will be combined with cognitive tests and brain scans to develop new, easy-to-use tools for detecting ADRD risk.

Who could benefit from this research

Good fit: This project focuses on older adults who are already participating in the Atherosclerosis Risk in Communities (ARIC) Neurocognitive Study.

Not a fit: Patients not currently enrolled in the ARIC Neurocognitive Study would not directly benefit from this specific data collection effort.

Why it matters

Potential benefit: If successful, this work could lead to new, non-invasive, and affordable ways to detect Alzheimer's disease and related dementias much earlier, allowing for timely interventions.

How similar studies have performed: Emerging research suggests links between digital signals and brain health, but this project aims to fill knowledge gaps by integrating these signals more comprehensively.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease detection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.