Using digital markers to detect cognitive decline in older adults

Life-Space and Activity Digital Markers for Detection of Cognitive Decline in Community-Dwelling Older Adults: The RAMS Study

NIH-funded research Virginia Commonwealth University · NIH-11052512

This study is looking at how digital tools can help spot early signs of memory problems in older adults, especially those at risk for Alzheimer's, by tracking their daily activities and movement patterns, so we can catch changes before they become serious and find ways to help.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-11052512 on NIH RePORTER

What this research studies

This research investigates how digital technology can help identify early signs of cognitive decline in older adults, particularly those at risk for Alzheimer's disease and related dementias. By using devices like GPS data loggers and wrist-worn actigraphy, the study aims to monitor real-life mobility and activity patterns. The goal is to develop practical markers that can signal changes in cognitive function before clinical symptoms appear, allowing for timely interventions. The study also considers the impact of social health factors, such as isolation and loneliness, on cognitive health.

Who could benefit from this research

Good fit: Ideal candidates for this research are community-dwelling adults aged 65 and older, particularly those who may be at risk for cognitive decline.

Not a fit: Patients under the age of 65 or those with established cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection of cognitive decline, allowing for interventions that may help maintain independence in older adults.

How similar studies have performed: Previous research has shown promise in using digital markers for monitoring health, suggesting that this approach could be effective in detecting cognitive decline.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.