NIH-funded research R01 grant

Using deep learning to find signs of cognitive impairment in health records

Official title: A deep learning algorithm to detect signs of cognitive impairment in electronic health records

Funded at Massachusetts General Hospital · NIH-11111272 · Data updated 2026-11-12

This study is working on a smart computer program called Decipher-AI that helps doctors spot signs of memory problems related to Alzheimer's and other dementias by looking at patients' health records, making it easier to catch these issues early and accurately.

More Cognitive Impairment research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startJune 15, 2024
Project endMay 31, 2029
Funding year2025
Award (this year)$405,398
NIH project number5R01AG082698-02
Project IDNIH-11111272 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals who have experienced cognitive concerns or are at risk for Alzheimer's disease and related dementias.

Less likely to help

Patients without any cognitive concerns or those who do not have access to electronic health records may not benefit from this research.

What this research studies

This research aims to develop a deep learning algorithm called Decipher-AI to improve the detection of cognitive impairment related to Alzheimer's disease and other dementias by analyzing electronic health records (EHR). The algorithm will utilize data from clinical notes, patient health histories, and health system interactions to identify patterns indicative of cognitive decline. By leveraging advanced natural language processing techniques, the study seeks to enhance the accuracy of cognitive impairment diagnoses, which are often missed or misclassified in traditional assessments.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of cognitive impairment, allowing for timely interventions and better management of Alzheimer's disease and related dementias.

How similar studies have gone: Other research has shown promise in using machine learning and deep learning approaches for improving diagnostic accuracy in various medical fields, suggesting potential success for this novel application.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Das, Sudeshna — Massachusetts General Hospital
  • Study coordinator: Das, Sudeshna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.