Using deep learning to find signs of cognitive impairment in health records

A deep learning algorithm to detect signs of cognitive impairment in electronic health records

NIH-funded research Massachusetts General Hospital · NIH-11111272

This study is working on a smart computer program called Decipher-AI that helps doctors spot signs of memory problems related to Alzheimer's and other dementias by looking at patients' health records, making it easier to catch these issues early and accurately.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11111272 on NIH RePORTER

What this research studies

This research aims to develop a deep learning algorithm called Decipher-AI to improve the detection of cognitive impairment related to Alzheimer's disease and other dementias by analyzing electronic health records (EHR). The algorithm will utilize data from clinical notes, patient health histories, and health system interactions to identify patterns indicative of cognitive decline. By leveraging advanced natural language processing techniques, the study seeks to enhance the accuracy of cognitive impairment diagnoses, which are often missed or misclassified in traditional assessments.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced cognitive concerns or are at risk for Alzheimer's disease and related dementias.

Not a fit: Patients without any cognitive concerns or those who do not have access to electronic health records may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of cognitive impairment, allowing for timely interventions and better management of Alzheimer's disease and related dementias.

How similar studies have performed: Other research has shown promise in using machine learning and deep learning approaches for improving diagnostic accuracy in various medical fields, suggesting potential success for this novel application.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.