NIH-funded research R03 grant

Using deep learning to analyze cancer treatment effectiveness

Official title: Cancer Emulation Analysis with Deep Neural Network

Funded at Yale University · NIH-10725293 · Data updated 2026-11-12

This study is exploring a new way to understand how well cancer treatments work by using advanced computer technology to analyze real-life medical data, which could help improve treatment options for older adults with cancer.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 19, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$167,500
NIH project number1R03CA276790-01A1
Project IDNIH-10725293 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults diagnosed with various types of cancer, including non-small cell lung cancer.

Less likely to help

Patients with early-stage cancers or those not receiving treatment may not benefit from this research.

What this research studies

This research aims to improve how we evaluate the effectiveness of cancer treatments by using advanced deep neural network techniques. Instead of relying solely on traditional randomized clinical trials, which can be difficult to conduct, the study will utilize large amounts of observational data from electronic medical records and insurance claims. By developing new software that employs deep learning, the researchers hope to create more accurate and interpretable models that can provide insights similar to those obtained from clinical trials. This approach could lead to better understanding and treatment options for various cancers, particularly in older adults.

Why it matters

Potential benefit: If successful, this research could lead to more effective cancer treatments tailored to individual patients, especially among the elderly.

How similar studies have gone: Previous research has shown success in using deep learning for emulation analysis in other complex diseases, indicating a promising approach for cancer treatment evaluation.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Ma, Shuangge — Yale University
  • Study coordinator: Ma, Shuangge

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.