Using deep brain stimulation to treat chronic low back pain
Deep Brain Stimulation of the Subgenual Cingulate Cortex for the Treatment of Medically Refractory Chronic Low Back Pain
This study is exploring how a special brain treatment called deep brain stimulation can help people with chronic low back pain who haven't found relief from regular treatments, and it aims to make the treatment more effective by personalizing it based on brain scans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10221068 on NIH RePORTER |
What this research studies
This research investigates the use of deep brain stimulation (DBS) targeting the subgenual cingulate cortex to alleviate chronic low back pain (CLBP) that has not responded to traditional treatments. The approach involves utilizing advanced DBS devices that can precisely target brain networks associated with pain perception and emotional response. By identifying neuroimaging biomarkers, the study aims to personalize treatment and improve outcomes for patients suffering from CLBP. Participants will be monitored for changes in pain levels and overall quality of life throughout the treatment process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic low back pain that has not improved with standard medical therapies.
Not a fit: Patients with low back pain resulting from identifiable structural issues that can be surgically corrected may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from chronic low back pain, potentially reducing reliance on opioids.
How similar studies have performed: Previous research has shown promise in using neuromodulation techniques for pain management, indicating potential for success with this novel approach.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Bari, Ausaf — University of California Los Angeles
- Study coordinator: Bari, Ausaf
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.