Using data science to understand long-term traumatic brain injury
Official title: Leveraging data-science for discovery in chronic TBI
Funded at Veterans Affairs Med Ctr San Francisco · NIH-11239759 · Data updated 2026-11-12
This project uses advanced data analysis to find patterns that explain long-term problems faced by people with chronic traumatic brain injury.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | October 1, 2018 |
| Project end | September 30, 2028 |
| Funding year | 2025 |
| NIH project number | 5I01RX002787-08 |
| Project ID | NIH-11239759 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with chronic traumatic brain injury — including veterans with blast-related injuries and civilians with long-standing symptoms — are the population this work aims to help.
✕Less likely to help
Patients with only a single recent acute concussion or whose symptoms come from unrelated medical conditions may not see direct benefit from this project.
What this research studies
This project brings together large datasets from animal experiments and related sources to spot patterns tied to long-term TBI symptoms. It uses new multidimensional analytics and big-data tools to connect findings across species and levels, from cells to behavior. By pooling many studies, the team hopes to find reproducible biological signatures that better predict disability and response to treatments. Work is based at the VA San Francisco and aims to improve how lab results translate into better care for people like you.
Why it matters
Potential benefit: If successful, this work could produce clearer biological targets and more reliable lab models, helping speed development of therapies for people with chronic TBI.
How similar studies have gone: Some big-data TBI projects have revealed useful patterns, but combining multidimensional animal and human-scale data for cross-species translation is a relatively new and still-developing approach.
Where this research is happening
-
Veterans Affairs Med Ctr San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Ferguson, Adam R — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Ferguson, Adam R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.