NIH-funded research U01 cooperative agreement

Using data science to improve health outcomes for children with HIV

Official title: DSpace: Utilizing Data Science to Predict and Improve Health Outcomes in Pediatric HIV

Funded at University of Botswana · NIH-10931535 · Data updated 2026-11-12

This study is looking to help children with HIV in sub-Saharan Africa by finding better ways to identify those at risk for Metabolic Syndrome and tuberculosis, so they can get the right care and support they need.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Botswana
NIH-funded
Lab location1 site (Gaborone, Botswana)
Project startSeptember 18, 2023
Project endAugust 31, 2026
Funding year2024
Award (this year)$235,948
NIH project number5U01HD114479-02
Project IDNIH-10931535 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include children aged 0-20 years who are infected with HIV and may be at risk for MetS or TB.

Less likely to help

Patients who are not infected with HIV or who are outside the age range of 0-20 years may not receive any benefit from this research.

What this research studies

This research focuses on addressing the rising rates of Metabolic Syndrome (MetS) and tuberculosis (TB) among children infected with HIV in sub-Saharan Africa. By utilizing advanced data science techniques, the project aims to enhance patient classification and risk stratification for these conditions, ultimately improving diagnosis and treatment outcomes. The study will analyze existing data to develop predictive models that can identify at-risk children and tailor interventions accordingly. This approach is particularly important given the unique challenges faced by pediatric populations in this region.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and better management of HIV-related complications in children.

How similar studies have gone: While there have been successful applications of data science in adult populations, this approach is novel in the context of pediatric HIV in sub-Saharan Africa.

Where this research is happening

  • University of Botswana
    Gaborone, Botswana
    Active

Researchers

  • Principal investigator: Retshabile, Gaone — University of Botswana
  • Study coordinator: Retshabile, Gaone

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.