Using daily movement patterns to protect brain health and prevent Alzheimer's disease

Leveraging the 24-hour movement paradigm to preserve cognitive function and prevent Alzheimer's disease: The Multi-Ethnic Study of Atherosclerosis (MESA) 24H-ACT Study

NIH-funded research Columbia University Health Sciences · NIH-10832998

This study is looking at how your daily activities, like moving around and sleeping, can affect your brain health and help prevent Alzheimer's, especially for Black and Hispanic communities, and we want to find out what kinds of movement and sleep are best for keeping your mind sharp.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10832998 on NIH RePORTER

What this research studies

This research investigates how different patterns of daily movement, including physical activity and sleep, can influence cognitive function and help prevent Alzheimer's disease, particularly in Black and Hispanic populations. The study aims to understand the impact of both sedentary behavior and light physical activity on brain health, as well as the effects of sleep quality and duration. By analyzing these factors, the research seeks to develop effective prevention strategies tailored to at-risk groups. Participants will be monitored for their movement and sleep patterns to gather comprehensive data on their health.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older, especially those from Black and Hispanic communities who may be at higher risk for Alzheimer's disease.

Not a fit: Patients who are not at risk for Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing cognitive decline and Alzheimer's disease, particularly for vulnerable populations.

How similar studies have performed: Previous research has shown that physical activity and sleep quality are important factors in cognitive health, suggesting that this approach could yield significant insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.