Using D3-Creatine to improve diagnosis of muscle wasting in cancer patients
Pre-clinical study for the use of D3-Creatine as a biomarker in cachexia clinical trials
This study is looking at how a substance called D3-Creatine might help doctors better diagnose muscle wasting in veterans with cancer, so they can find more effective treatments and improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Edward Hines Jr VA Hospital NIH-funded |
| Lab location | 1 site (Hines, United States) |
| Project ID | NIH-10916607 on NIH RePORTER |
What this research studies
This research investigates the potential of D3-Creatine as a biomarker to accurately diagnose muscle wasting disorders, specifically cachexia, in veterans with cancer. The study aims to address the limitations of current diagnostic methods, which often fail to provide precise assessments of muscle mass and function. By conducting pre-clinical tests, the researchers hope to establish a reliable correlation between D3-Creatine levels and muscle health, ultimately improving the classification of muscle wasting in cancer patients. This could lead to better-targeted treatments and improved patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with cancer who are experiencing symptoms of muscle wasting or cachexia.
Not a fit: Patients who do not have cancer or muscle wasting disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses of muscle wasting in cancer patients, allowing for better treatment strategies and improved quality of life.
How similar studies have performed: While D3-Creatine has shown promise in other contexts, its application specifically for cancer-related muscle wasting is still under investigation and has not been widely tested.
Where this research is happening
Hines, United States
- Edward Hines Jr VA Hospital — Hines, United States (Active)
Researchers
- Principal investigator: Lieber, Richard L. — Edward Hines Jr VA Hospital
- Study coordinator: Lieber, Richard L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.