Using CT calcium scores to predict heart failure risk

Radiomics-based risk prediction of heart failure using CT calcium score exam

NIH-funded research Case Western Reserve University · NIH-11049497

This study is looking at how CT calcium score exams can help predict the risk of heart failure in people who are already getting these scans for heart health, with the goal of finding ways to identify those who might need earlier treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11049497 on NIH RePORTER

What this research studies

This research investigates how CT calcium score exams can be used to predict the risk of heart failure in patients. By analyzing data from large cohorts, including those already undergoing CT scans for cardiovascular assessments, the study aims to develop a model that identifies individuals at high risk for heart failure. The approach utilizes advanced radiomics techniques, which involve extracting and analyzing features from medical images to improve risk prediction accuracy. This could lead to earlier interventions and personalized treatment strategies for those at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have undergone or are scheduled for a CT calcium score exam and are at risk for heart failure.

Not a fit: Patients who do not have a CT calcium score exam or those with existing heart failure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enable earlier identification and prevention of heart failure, potentially reducing morbidity and mortality associated with the condition.

How similar studies have performed: Previous research has shown promise in using imaging techniques for cardiovascular risk assessment, suggesting that this approach could be effective.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.