Using CT calcium scores to predict heart failure risk
Official title: Radiomics-based risk prediction of heart failure using CT calcium score exam
Funded at Case Western Reserve University · NIH-11049497 · Data updated 2026-11-12
This study is looking at how CT calcium score exams can help predict the risk of heart failure in people who are already getting these scans for heart health, with the goal of finding ways to identify those who might need earlier treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | December 12, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $742,395 |
| NIH project number | 1R01HL173186-01A1 |
| Project ID | NIH-11049497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have undergone or are scheduled for a CT calcium score exam and are at risk for heart failure.
✕Less likely to help
Patients who do not have a CT calcium score exam or those with existing heart failure may not benefit from this research.
What this research studies
This research investigates how CT calcium score exams can be used to predict the risk of heart failure in patients. By analyzing data from large cohorts, including those already undergoing CT scans for cardiovascular assessments, the study aims to develop a model that identifies individuals at high risk for heart failure. The approach utilizes advanced radiomics techniques, which involve extracting and analyzing features from medical images to improve risk prediction accuracy. This could lead to earlier interventions and personalized treatment strategies for those at risk.
Why it matters
Potential benefit: If successful, this research could enable earlier identification and prevention of heart failure, potentially reducing morbidity and mortality associated with the condition.
How similar studies have gone: Previous research has shown promise in using imaging techniques for cardiovascular risk assessment, suggesting that this approach could be effective.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Li, Shuo — Case Western Reserve University
- Study coordinator: Li, Shuo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.