Using CRISPR technology for advanced imaging of cells
Official title: CRISPR-Image Core
Funded at South Dakota State University · NIH-11035170 · Data updated 2026-11-12
This study is using a special tool called CRISPR to change genes in cells to help scientists learn more about how immune and inflammatory cells work, and it’s designed for researchers who want to better understand these important processes in our bodies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | South Dakota State University NIH-funded |
| Lab location | 1 site (Brookings, United States) |
| Project start | March 20, 2022 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $353,282 |
| NIH project number | 5P20GM135008-04 |
| Project ID | NIH-11035170 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions influenced by immune system functions or inflammatory processes.
✕Less likely to help
Patients with conditions unrelated to immune or inflammatory responses may not receive any benefit from this research.
What this research studies
This research focuses on utilizing CRISPR technology to edit genes in mammalian cells and employing high-resolution optical imaging to analyze cellular and molecular characteristics. By creating targeted gene knockouts and expressing fluorescent proteins, the project aims to enhance our understanding of immune and inflammatory cells. The CRISPR-IMAGE Core will provide essential resources for researchers to conduct genotype-to-phenotype analysis, enabling rapid and detailed examination of cellular functions and structures. This innovative approach combines molecular biology with advanced microscopy techniques to push the boundaries of bioscience.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding and treating diseases related to immune and inflammatory responses.
How similar studies have gone: Other research utilizing CRISPR technology and advanced imaging has shown promising results, indicating that this approach is both innovative and grounded in successful methodologies.
Where this research is happening
-
South Dakota State University
Brookings, United States Active
Researchers
- Principal investigator: Hoppe, Adam David — South Dakota State University
- Study coordinator: Hoppe, Adam David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.