Using CPAP therapy to help lung growth in preterm infants
Official title: Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function: A Randomized Controlled Trial
Funded at Oregon Health & Science University · NIH-10683051 · Data updated 2026-11-12
This study is looking at whether keeping stable preterm babies on CPAP breathing support for two extra weeks can help their lungs grow better and work more effectively, so they can breathe easier as they grow.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 28, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $643,913 |
| NIH project number | 5R33HL147906-05 |
| Project ID | NIH-10683051 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are stable preterm infants who meet specific criteria for CPAP therapy continuation in the NICU.
✕Less likely to help
Patients who are not preterm or who do not require CPAP therapy will not benefit from this research.
What this research studies
This research investigates the effects of extending continuous positive airway pressure (CPAP) therapy in stable preterm infants to enhance lung growth and function. The study aims to determine if keeping infants on CPAP for an additional two weeks can improve their lung capacity and overall respiratory health compared to those who have CPAP discontinued earlier. By randomizing infants based on specific stability criteria, the research seeks to gather evidence on the optimal duration of CPAP therapy in the neonatal intensive care unit (NICU). This could lead to better management of lung development in preterm infants.
Why it matters
Potential benefit: If successful, this research could significantly improve lung growth and function in preterm infants, reducing respiratory complications later in life.
How similar studies have gone: Previous studies have shown promising results with CPAP therapy in preterm infants, but this specific approach of extending therapy duration is novel.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Mcevoy, Cynthia T — Oregon Health & Science University
- Study coordinator: Mcevoy, Cynthia T
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.