Using computer models to improve vein graft success after heart surgery
Computational model-driven design to mitigate vein graft failure after coronary artery bypass
['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10895578
This study is looking for ways to help heart surgery patients by finding out how special coverings can keep vein grafts from failing after surgery, making the recovery process smoother and more successful.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10895578 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the success of saphenous vein grafts used in coronary artery bypass graft (CABG) surgery. By utilizing advanced computational models, the study aims to understand the mechanical factors that lead to vein graft failure. The researchers will simulate various conditions to identify how external bioabsorbable sheaths can be used post-surgery to reduce the risk of graft failure. This innovative approach seeks to provide a more effective solution for patients undergoing CABG.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients scheduled for coronary artery bypass graft surgery who will receive saphenous vein grafts.
Not a fit: Patients who are not undergoing CABG surgery or those who do not require vein grafts may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rates of vein graft failure, improving outcomes for patients undergoing heart surgery.
How similar studies have performed: Other research has shown promise in using computational models to predict and improve surgical outcomes, indicating that this approach may lead to significant advancements.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARSDEN, ALISON L — STANFORD UNIVERSITY
- Study coordinator: MARSDEN, ALISON L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.